Package details: 

1) 1~10kg/bag, aluminum foil bag. 
2) 25kg/cardboard drum for large cargo. 
3) According to customers' requirements.

Description of product:

Mangiferin has been isolated from the leaves of Mangifera indica L. Showing antioxidative, antiviral, and anticancer effect. 

An in vivo microdialysis sampling method coupled to microbore high-performance liquid chromatography was employed 

for continuous monitoring of free mangiferin in rat blood.

Mango Leaf Extract( Mangiferin )contains a lot of glucosides, such as Mangiferin, Isomangiferin, Neomangiferin, Homomangiferin etc. 

The Mangiferin is most and key active ingredient in these glucosides. Our Mangiferin is extracted from fresh or dry mango leaves. 

It will contains a very little quantity of Isomangiferin, Neomangiferin, Homomangiferin etc. If you have limit on content of Isomangiferin, 

Neomangiferin, Homomangiferin, please advise when you buy from us.

Main functions:

1. With obvious central nervous system excitability: Intraperitoneal injection of mangiferin (JP) resulted in symptoms of motor tremor, 

vertical hair, forced tearing and increased autonomic activity in all subjects. The peak of these behavioral changes after 30min of administration 

and maintain to 60min, it  gradually decreased after 120min.

2. Anti-viral: Mangiferin has the effect of anti herpes simplex virus type 1 (HSV- I) in vitro, and the rate of plaque reduction is 56.8%. 

Its antiviral effect is attributed to its ability to inhibit viral replication in cells.

3. Radiation resistance: Mangiferin is a natural antioxidant that free radical scavenging. It is also a natural radiation protective agent, 

4 phenolic hydroxyl groups in the molecular structure of the electrophilic ability and benzene is good energy trap, 

therefore biological molecules by irradiation induced free radical transfer of a set, so it can protect the biological molecular.

4. Anti-tumor: In normal, vivo or vitro mice treated with tumor, Mangiferin can improve cytotoxicity of spleen cells and peritoneal macrophages. 

Mangiferin could effectively inhibit the inhibition of adriamycin (Dox) on cytochrome C oxidase in mitochondria, and had no effect on the antitumor activity of Dox.

5. Anti-diabetic: Oral administration of Mangiferin and its glucoside, no change of blood glucose level in normal mice, 

but it could decrease the blood glucose concentration in spontaneous diabetic animal model of KK-Ay mice and serum insulin levels also decreased. 

Intraperitoneal injection of Mangiferin, can reduce diabetic rats caused by oxidative damage of glycosylated hemoglobin and serum creatine phosphokinase (the amount of CPK).

6. Others: Mangiferin has antibacterial, anti-inflammatory, antipyretic and immunomodulatory effects. Pharmacological effects of Mangiferin is clear; 

plant sources are widely. At present the main clinical application is use in respiratory diseases. 

Although the Mangiferin has limitation in clinical application because of poor performance due to its solubility,

 but its anticancer, antiviral and anti diabetes activity has been paid more and more attention with the research. 

Further, Mangiferin will have good prospects for development.

Application of Mangiferin Mango Extract:

1) Pharmaceutical usage;

2) Functional food usage;

3) Water-soluble beverages;

4) Health products. 

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